Presentations Will Focus on Probabilistic Genotyping, LR Behavior of Y-STR Profiles
The results will demonstrate that the HC-LR decreases appropriately as uncertainty in the contributing haplotypes increases. As the information in the sample decreases, the LRs trend toward one.”— Dr. Hannah Kelly WASHINGTON, DC, UNITED STATES, August 14, 2026 /EINPresswire.com/ — STRmix will maintain a significant presence when the International Society for Forensic Genetics (ISFG)—an international organization dedicated to advancing scientific knowledge of genetic markers used in forensic analysis—holds its 31st Congress in Montréal from August 17–21.
Beyond its exhibition booth, STRmix team members will deliver a talk titled “Likelihood Ratio Behavior for Mixed and Low Template Y-STR Samples in the Haplotype-Centered Method” as part of the Congress Program, and they will also take part in a Poster Session on “Probabilistic Genotyping of Y-STR Profiles.”
Founded in 1968, ISFG represents over 1,100 members from more than 60 countries. Its regular meetings—conducted at both regional and international levels—are intended to offer a thorough survey of the newest scientific advancements, technological breakthroughs, and practical field applications.
Participants at the 31st ISFG Congress can look forward to a vibrant mix of plenary sessions, keynote presentations, panel discussions, workshops, and poster sessions, all designed to encourage knowledge exchange and interdisciplinary collaboration.
The STRmix Poster Session, “Probabilistic Genotyping of Y-STR Profiles,” will examine whether a probabilistic genotyping approach can tackle the difficulties linked to interpreting Y-STR profiles, especially in complex mixtures involving multiple male contributors. These difficulties are compounded by the absence of consensus-driven interpretation standards and by the variability in how laboratories handle stochastic effects, PCR artifacts, and multi-copy loci, which introduces subjectivity in reported casework.
Presented by Emma Marie, Data Analyst at STRmix, the poster session will share early outcomes from a sensitivity and specificity study covering a range of mixed Y-STR profiles of differing quality and quantity. This Poster Session is scheduled for Wednesday, August 19, starting at 10:49 a.m.
On the final day of the ISFG Congress, August 21, the talk “Likelihood Ratio Behavior for Mixed and Low Template Y-STR Samples in the Haplotype-Centered Method” will take place at 12:15 p.m. Delivered by STRmix Science Leader Dr. Hannah Kelly, this presentation will provide findings on the Haplotype Centered Likelihood Ratio (HC-LR), a technique that enables locus-specific haplotype weights to be integrated into a likelihood ratio for Y-STR data.
According to Dr. Kelly, the findings “will demonstrate that the HC-LR decreases appropriately as uncertainty in the contributing haplotypes increases. As the information in the sample decreases, the likelihood ratios trend toward one. This highlights the suitability of the method for integration with a probabilistic Y-STR interpretation framework.”
Since its launch in 2012, STRmix™ has proven to be a highly effective tool for generating usable, interpretable, and admissible DNA results in more than 700,000 criminal cases worldwide. It has been particularly useful in resolving violent crime and sexual assault cases, as well as cold cases where evidence was initially dismissed as inconclusive.
The global success of STRmix™ has prompted the team behind its development to create and regularly update three related software applications:
• FaSTR™ DNA, expert forensic software that integrates seamlessly with STRmix™ (when in use) to rapidly analyze raw DNA data and assign a number of contributors (NoC) estimate;
• DBLR™, an application that, when used with STRmix™, allows forensic laboratories to conduct extensive kinship analysis, perform rapid database searches and mixture-to-mixture matches, and visualize the value of their DNA mixture evidence;
• STRmix™ NGS, fully continuous mixture interpretation and likelihood ratio generation software designed for profiles generated through Next Generation Sequencing.
Together with STRmix™, FaSTR™ DNA and DBLR™ complete the full workflow from analysis to interpretation and database matching, while STRmix™ NGS expands the range of profile types that can be interpreted.
For additional details about ISFG, visit https://isfg2026.ca/. For more information about STRmix™, visit http://www.strmix.com.
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